Gerald Falchook: search on Z-Library

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1

Pharmacokinetic evaluation of nanoparticle albumin-bound paclitaxel delivered via hepatic arterial infusion in patients with predominantly hepatic metastases

Siqing, Fu, Culotta, Kirk S., Falchook, Gerald S., Hong, David S., Myers, Alan L., Zhang, Yan-Ping, Naing, Aung, Janku, Filip, Hou, Ming-Mo, Kurzrock, Razelle

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 529 KB

english, 2016

2

Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial

Maitland, Michael L., Piha-Paul, Sarina, Falchook, Gerald, Kurzrock, Razelle, Nguyen, Ly, Janisch, Linda, Karovic, Sanja, McKee, Mark, Hoening, Elizabeth, Wong, Shekman, Munasinghe, Wijith, Palma, Joa

Journal:

British Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 738 KB

english, 2018

3

Prevalence of complementary medicine use in a phase 1 clinical trials program : The MD Anderson Cancer Center Experience

Aung Naing, Saneese K. Stephen, Moshe Frenkel, Chandtip Chandhasin, David S. Hong, Xiudong Lei, Gerald Falchook, Jennifer J. Wheler, Siqing Fu, Razelle Kurzrock

Journal:

Year:

2011

Language:

english

File:

PDF, 143 KB

english, 2011

4

Validation of the royal marsden hospital prognostic score in patients treated in the phase I clinical trials program at the MD Anderson Cancer Center

Ignacio Garrido-Laguna, Filip Janku, Christos Vaklavas, Gerald S. Falchook, Siqing Fu, David S. Hong, Aung Naing, Apostolia M. Tsimberidou, Sijin Wen, Razelle Kurzrock

Journal:

Year:

2012

Language:

english

File:

PDF, 924 KB

english, 2012

5

Phase I trial of oral talactoferrin alfa in refractory solid tumors

Teresa G. Hayes, Gerald F. Falchook, Gauri R. Varadhachary, Dori P. Smith, Lisa D. Davis, Hari M. Dhingra, Benjamin P. Hayes, Atul Varadhachary

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 220 KB

english, 2006

6

Phase IB trial of oral talactoferrin in the treatment of patients with metastatic solid tumors

Teresa G. Hayes, Gerald S. Falchook, Atul Varadhachary

Journal:

Investigational New Drugs

Year:

2010

Language:

english

File:

PDF, 195 KB

english, 2010

7

Clinicopathologic features and treatment strategies for patients with pancreatic adenocarcinoma and ovarian metastases

Gerald S. Falchook, Robert A. Wolff, Gauri R. Varadhachary

Journal:

Gynecologic Oncology

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

8

Phase I clinical trials in 85 patients with gynecologic cancer: The M. D. Anderson Cancer Center experience

John Moroney, Jennifer Wheler, David Hong, Aung Naing, Gerald Falchook, Diane Bodurka, Robert Coleman, Karen Lu, Lianchun Xiao, Razelle Kurzrock

Journal:

Gynecologic Oncology

Year:

2010

Language:

english

File:

PDF, 446 KB

english, 2010

9

Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial

Gerald S Falchook, Georgina V Long, Razelle Kurzrock, Kevin B Kim, Tobias H Arkenau, Michael P Brown, Omid Hamid, Jeffrey R Infante, Michael Millward, Anna C Pavlick, Steven J O’Day, Samuel C Blackman

Journal:

Year:

2012

Language:

english

File:

PDF, 576 KB

english, 2012

10

Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial

Jeffrey R Infante, Leslie A Fecher, Gerald S Falchook, Sujatha Nallapareddy, Michael S Gordon, Carlos Becerra, Douglas J DeMarini, Donna S Cox, Yanmei Xu, Shannon R Morris, Vijay GR Peddareddigari, Ng

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 246 KB

english, 2012

11

Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial

Gerald S Falchook, Karl D Lewis, Jeffrey R Infante, Michael S Gordon, Nicholas J Vogelzang, Douglas J DeMarini, Peng Sun, Christopher Moy, Stephen A Szabo, Lori T Roadcap, Vijay GR Peddareddigari, Pet

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 225 KB

english, 2012

12

Trametinib for patients with advanced melanoma – Authors' reply

Gerald S Falchook, Christopher Moy, Douglas J DeMarini

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 45 KB

english, 2012

13

Phase I clinical trial of lenalidomide in combination with sorafenib in patients with advanced cancer

Prasanth Ganesan, Sarina Piha-Paul, Aung Naing, Gerald Falchook, Jennifer Wheler, Siqing Fu, David S. Hong, Razelle Kurzrock, Filip Janku, Shell Laday, Agop Y. Bedikian, Merrill Kies, Robert A. Wolff,

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 258 KB

english, 2014

14

A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors

David S. Hong, Jennifer Hsing Choe, Aung Naing, Jennifer J. Wheler, Gerald S. Falchook, Sarina Piha-Paul, Stacy L. Moulder, Goldy C. George, Jonathan M. Choe, Lewis C. Strauss, Gary E. Gallick, Razell

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 335 KB

english, 2013

15

Phase I clinical trial of lenalidomide in combination with temsirolimus in patients with advanced cancer

Ganesan, Prasanth, Piha-Paul, Sarina, Naing, Aung, Falchook, Gerald, Wheler, Jennifer, Janku, Filip, Zinner, Ralph, Laday, Shell, Kies, Merrill, Tsimberidou, Apostolia M.

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 341 KB

english, 2013

16

Phase I study of anti-VEGF monoclonal antibody bevacizumab and histone deacetylase inhibitor valproic acid in patients with advanced cancers

Wheler, Jennifer J., Janku, Filip, Falchook, Gerald S., Jackson, Tiffiny L., Fu, Siqing, Naing, Aung, Tsimberidou, Apostalia M., Moulder, Stacy L., Hong, David S., Yang, Hui, Piha-Paul, Sarina A., Atk

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 386 KB

english, 2014

17

Phase I dose-escalating study of TAS-106 in combination with carboplatin in patients with solid tumors

Naing, Aung, Fu, Siqing, Zinner, Ralph G., Wheler, Jennifer J., Hong, David S., Arakawa, Kazuhito, Falchook, Gerald S., Kurzrock, Razelle

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 147 KB

english, 2014

18

Transient severe hyperbilirubinemia after hepatic arterial infusion of oxaliplatin in patients with liver metastases

Garcia, Sean S., Atkins, Johnique T., Falchook, Gerald S., Tsimberidou, Apostolia M., Hong, David S., Trivedi, Meghana V., Kurzrock, Razelle

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 301 KB

english, 2013

19

Su1015 Transient Severe Hyperbilirubinemia After Hepatic Arterial Infusion of Oxaliplatin in Patients With Liver Metastases

Garcia, Sean S., Atkins, Johnique T., Falchook, Gerald S., Tsimberidou, Apostolia M., Hong, David S., Trivedi, Meghana V., Kurzrock, Razelle

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 103 KB

english, 2013

20

Assessing PIK3CA and PTEN in Early-Phase Trials with PI3K/AKT/mTOR Inhibitors

Janku, Filip, Hong, David S., Fu, Siqing, Piha-Paul, Sarina A., Naing, Aung, Falchook, Gerald S., Tsimberidou, Apostolia M., Stepanek, Vanda M., Moulder, Stacy L., Lee, J. Jack, Luthra, Rajyalakshmi,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

21

MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study

Hong, David S, Hui, David, Bruera, Eduardo, Janku, Filip, Naing, Aung, Falchook, Gerald S, Piha-Paul, Sarina, Wheler, Jennifer J, Fu, Siqing, Tsimberidou, Apostolia M, Stecher, Michael, Mohanty, Prasa

Journal:

The Lancet Oncology

Year:

2014

Language:

english

File:

PDF, 330 KB

english, 2014

22

Outcomes in 144 Patients With Colorectal Cancer Treated in a Phase I Clinic: The MD Anderson Cancer Center Experience

Hong, David S., Patel, Jesal C., Wheler, Jennifer, Naing, Aung, Garrido-Laguna, Ignacio, Falchook, Gerald, Fu, Siqing, Tsimberidou, Apostolia M., Kopetz, Scott, Win, Sijin, Kurzrock, Razelle

Journal:

Clinical Colorectal Cancer

Year:

2012

Language:

english

File:

PDF, 472 KB

english, 2012

23

Phase 1, open-label, dose-escalation, and pharmacokinetic study of STAT3 inhibitor OPB-31121 in subjects with advanced solid tumors

Bendell, Johanna C., Hong, David S., Burris, Howard A., Naing, Aung, Jones, Suzanne F., Falchook, Gerald, Bricmont, Patricia, Elekes, Agnes, Rock, Edwin P., Kurzrock, Razelle

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 189 KB

english, 2014

24

Exploratory study of carboplatin plus the copper-lowering agent trientine in patients with advanced malignancies

Fu, Siqing, Hou, Ming-Mo, Wheler, Jennifer, Hong, David, Naing, Aung, Tsimberidou, Apostolia, Janku, Filip, Zinner, Ralph, Piha-Paul, Sarina, Falchook, Gerald, Kuo, Macus Tien, Kurzrock, Razelle

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 480 KB

english, 2014

25

Evaluation of a novel blood pressure scoring method and its association with clinical response in cancer patients treated with anti-vascular endothelial growth factor therapy

Bilen, Mehmet Asim, Durand, Jean-Bernard, McQuinn, Lacey, Hess, Kenneth R., Fu, Siqing, Falchook, Gerald S., Hong, David S., Wheler, Jennifer J., Said, Rabih, Ewer, Michael S., Kurzrock, Razelle, Nain

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 187 KB

english, 2014

26

Methylation and histone deacetylase inhibition in combination with platinum treatment in patients with advanced malignancies

Falchook, Gerald S., Fu, Siqing, Naing, Aung, Hong, David S., Hu, Wei, Moulder, Stacy, Wheler, Jennifer J., Sood, Anil K., Bustinza-Linares, Ernesto, Parkhurst, Kristin L., Kurzrock, Razelle

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 274 KB

english, 2013

27

Investigational Aurora A kinase inhibitor alisertib (MLN8237) as an enteric-coated tablet formulation in non-hematologic malignancies: Phase 1 dose-escalation study

Falchook, Gerald, Kurzrock, Razelle, Gouw, Launce, Hong, David, McGregor, Kimberly A., Zhou, Xiaofei, Shi, Hongliang, Fingert, Howard, Sharma, Sunil

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 856 KB

english, 2014

28

Dual inhibition of the vascular endothelial growth factor pathway: A phase 1 trial evaluating bevacizumab and AZD2171 (cediranib) in patients with advanced solid tumors

Hong, David S., Garrido-Laguna, Ignacio, Ekmekcioglu, Suhendan, Falchook, Gerald S., Naing, Aung, Wheler, Jennifer J., Fu, Siqing, Moulder, Stacy L., Piha-Paul, Sarina, Tsimberidou, Apostolia M., Wen,

Journal:

Year:

2014

Language:

english

File:

PDF, 349 KB

english, 2014

29

MET Abnormalities in Patients With Genitourinary Malignancies and Outcomes With c-MET Inhibitors

Jardim, Denis L.F., de Melo Gagliato, Débora, Falchook, Gerald, Zinner, Ralph, Wheler, Jennifer J., Janku, Filip, Subbiah, Vivek, Piha-Paul, Sarina A., Fu, Siqing, Tannir, Nizar, Corn, Paul, Tang, Cha

Journal:

Clinical Genitourinary Cancer

Year:

2015

Language:

english

File:

PDF, 506 KB

english, 2015

30

Analysis of MET Genetic Aberrations in Patients With Breast Cancer at MD Anderson Phase I Unit

de Melo Gagliato, Debora, Jardim, Denis L. Fontes, Falchook, Gerald, Tang, Chad, Zinner, Ralph, Wheler, Jennifer J., Janku, Filip, Subbiah, Vivek, Piha-Paul, Sarina A., Fu, Siqing, Hess, Kenneth, Roy-

Journal:

Clinical Breast Cancer

Year:

2014

Language:

english

File:

PDF, 234 KB

english, 2014

31

BRAF Inhibitor Dabrafenib in Patients with Metastatic BRAF -Mutant Thyroid Cancer

Falchook, Gerald S., Millward, Michael, Hong, David, Naing, Aung, Piha-Paul, Sarina, Waguespack, Steven G., Cabanillas, Maria E., Sherman, Steven I., Ma, Bo, Curtis, Martin, Goodman, Vicki, Kurzrock,

Journal:

Year:

2015

Language:

english

File:

PDF, 669 KB

english, 2015

32

Human epidermal receptor 2-amplified salivary duct carcinoma: Regression with dual human epidermal receptor 2 inhibition and anti-vascular endothelial growth factor combination treatment

Falchook, Gerald S., Lippman, Scott M., Bastida, Christel C., Kurzrock, Razelle

Journal:

Year:

2014

Language:

english

File:

PDF, 127 KB

english, 2014

33

Dual antiangiogenic inhibition: a phase I dose escalation and expansion trial targeting VEGF-A and VEGFR in patients with advanced solid tumors

Falchook, Gerald S., Wheler, Jennifer J., Naing, Aung, Piha-Paul, Sarina A., Fu, Siqing, Tsimberidou, Apostolia M., Hong, David S., Janku, Filip, Zinner, Ralph, Jiang, Yunfang, Huang, Mei, Lin, Quan,

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 652 KB

english, 2015

34

Olanzapine for cachexia in patients with advanced cancer: an exploratory study of effects on weight and metabolic cytokines

Naing, Aung, Dalal, Shalini, Abdelrahim, Maen, Wheler, Jennifer, Hess, Kenneth, Fu, Siqing, Hong, David S., Janku, Filip, Falchook, Gerald S., Ilustre, Alyson, Ouyang, Fengying, Kurzrock, Razelle

Journal:

Supportive Care in Cancer

Year:

2015

Language:

english

File:

PDF, 345 KB

english, 2015

35

A phase I trial of combination trastuzumab, lapatinib, and bevacizumab in patients with advanced cancer

Falchook, Gerald S., Moulder, Stacy, Naing, Aung, Wheler, Jennifer J., Hong, David S., Piha-Paul, Sarina A., Tsimberidou, Apostolia M., Fu, Siqing, Zinner, Ralph, Janku, Filip, Jiang, Yunfang, Huang,

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 362 KB

english, 2015

36

VEGF and dual-EGFR inhibition in colorectal cancer

Falchook, Gerald S, Kurzrock, Razelle

Journal:

Year:

2015

Language:

english

File:

PDF, 462 KB

english, 2015

37

Phase I trial of valproic acid and lenalidomide in patients with advanced cancer

Bilen, Mehmet Asim, Fu, Siqing, Falchook, Gerald S., Ng, Chaan S., Wheler, Jennifer J., Abdelrahim, Maen, Erguvan-Dogan, Basak, Hong, David S., Tsimberidou, Apostolia M., Kurzrock, Razelle, Naing, Aun

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 359 KB

english, 2015

38

Xilonix, a novel true human antibody targeting the inflammatory cytokine interleukin-1 alpha, in non-small cell lung cancer

Hong, David S., Janku, Filip, Naing, Aung, Falchook, Gerald S., Piha-Paul, Sarina, Wheler, Jennifer J., Fu, Siqing, Tsimberidou, Apostolia M., Stecher, Michael, Mohanty, Prasant, Simard, John, Kurzroc

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 713 KB

english, 2015

39

Next generation sequencing of exceptional responders with BRAF-mutant melanoma: implications for sensitivity and resistance

Wheler, Jennifer, Yelensky, Roman, Falchook, Gerald, Kim, Kevin B, Hwu, Patrick, Tsimberidou, Apostolia M, Stephens, Philip J, Hong, David, Cronin, Maureen T, Kurzrock, Razelle

Journal:

Year:

2015

Language:

english

File:

PDF, 995 KB

english, 2015

40

Phase I study of azacitidine and oxaliplatin in patients with advanced cancers that have relapsed or are refractory to any platinum therapy

Tsimberidou, Apostolia M, Said, Rabih, Culotta, Kirk, Wistuba, Ignacio, Jelinek, Jaroslav, Fu, Siqing, Falchook, Gerald, Naing, Aung, Piha-Paul, Sarina, Zinner, Ralph, Siddik, Zahid H, He, Guangan, He

Journal:

Clinical Epigenetics

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

41

Nivolumab: another weapon in the growing immunotherapy arsenal

Falchook, Gerald

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 201 KB

english, 2015

42

Dabrafenib for treatment of BRAF-mutant melanoma

Falchook, Gerald, Kainthla, Radhika, Kim, Kevin

Journal:

Pharmacogenomics and Personalized Medicine

Year:

2013

Language:

english

File:

PDF, 314 KB

english, 2013

43

Aurora Kinase Inhibitors in Oncology Clinical Trials: Current State of the Progress

Falchook, Gerald S., Bastida, Christel C., Kurzrock, Razelle

Journal:

Seminars in Oncology

Year:

2015

Language:

english

File:

PDF, 764 KB

english, 2015

44

Phase I clinical trial of lenalidomide in combination with 5-fluorouracil, leucovorin, and oxaliplatin in patients with advanced cancer

Said, Rabih, Ye, Yang, Hong, David S., Naing, Aung, Falchook, Gerald, Fu, Siqing, Wheler, Jennifer J., Piha-Paul, Sarina, Tsimberidou, Apostolia-Maria

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 604 KB

english, 2016

45

Erratum to: Pharmacokinetic evaluation of nanoparticle albumin-bound paclitaxel delivered via hepatic arterial infusion in patients with predominantly hepatic metastases

Fu, Siqing, Culotta, Kirk S., Falchook, Gerald S., Hong, David S., Myers, Alan L., Zhang, Yan-Ping, Naing, Aung, Janku, Filip, Hou, Ming-Mo, Kurzrock, Razelle

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 352 KB

english, 2016

46

Phase I clinical trial of lenalidomide in combination with bevacizumab in patients with advanced cancer

Said, Rabih, Kakadiaris, Eugenia, Piha-Paul, Sarina, Fu, Siqing, Falchook, Gerald, Janku, Filip, Wheler, Jennifer J., Zinner, Ralph, Hong, David S., Kurzrock, Razelle, Tsimberidou, Apostolia M.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 430 KB

english, 2016

47

Effect of Food on the Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237) in Patients with Advanced Solid Tumors

Falchook, Gerald S., Zhou, Xiaofei, Venkatakrishnan, Karthik, Kurzrock, Razelle, Mahalingam, Devalingam, Goldman, Jonathan W., Jung, JungAh, Ullmann, Claudio Dansky, Milch, Catherine, Rosen, Lee S., S

Journal:

Year:

2016

Language:

english

File:

PDF, 793 KB

english, 2016

48

Association between new-onset hypothyroidism and clinical response in patients treated with tyrosine kinase inhibitor therapy in phase I clinical trials

Bilen, Mehmet Asim, Patel, Amy, Hess, Kenneth R., Munoz, Javier, Busaidy, Naifa L., Wheler, Jennifer J., Janku, Filip, Falchook, Gerald S., Hong, David S., Meric-Bernstam, Funda, Habra, Mouhammed Amir

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 418 KB

english, 2016

49

Changes in Tumor Morphology and Cyclin-Dependent Kinase Inhibitor Expression in Metastatic Melanoma Treated With Selective Second-Generation BRAF Inhibitor

Curry, Jonathan L., Falchook, Gerald S., Hwu, Wen-Jen, Torres-Cabala, Carlos A., Duvic, Madeleine, Tetzlaff, Michael T., Prieto, Victor G.

Journal:

American Journal of Dermatopathology

Year:

2013

Language:

english

File:

PDF, 537 KB

english, 2013

50

Pharmacokinetics of ixazomib, an oral proteasome inhibitor, in solid tumour patients with moderate or severe hepatic impairment

Gupta, Neeraj, Hanley, Michael J., Venkatakrishnan, Karthik, Perez, Raymond, Norris, Robin E., Nemunaitis, John, Yang, Huyuan, Qian, Mark G., Falchook, Gerald, Labotka, Richard, Fu, Siqing

Journal:

British Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 670 KB

english, 2016

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